Evidence Library

Landmark Clinical Trials

The evidence that guides every WhiteGloveMD second opinion. 20 trials reviewed and summarized by our Heart Team.

Valve2019

PARTNER 3

Placement of Aortic Transcatheter Valves 3

New England Journal of Medicine

Valve2011

PARTNER 1

Placement of Aortic Transcatheter Valves 1

New England Journal of Medicine

Valve2016

PARTNER 2

Placement of Aortic Transcatheter Valves 2

New England Journal of Medicine

Valve2019

Evolut Low Risk

Medtronic Evolut Transcatheter Aortic Valve Replacement in Low-Risk Patients

New England Journal of Medicine

Coronary2009

SYNTAX

Synergy Between PCI with Taxus and Cardiac Surgery

New England Journal of Medicine

Coronary2012

FREEDOM

Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease

New England Journal of Medicine

Coronary2019

EXCEL

Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization

New England Journal of Medicine

Coronary2020

ISCHEMIA

International Study of Comparative Health Effectiveness with Medical and Invasive Approaches

New England Journal of Medicine

Valve2018

COAPT

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation

New England Journal of Medicine

Valve2018

MITRA-FR

Percutaneous Repair with the MitraClip Device for Severe Functional/Secondary Mitral Regurgitation

New England Journal of Medicine

Arrhythmia2018

CASTLE-AF

Catheter Ablation versus Standard Conventional Therapy in Patients with Left Ventricular Dysfunction and Atrial Fibrillation

New England Journal of Medicine

Arrhythmia2019

CABANA

Catheter Ablation versus Antiarrhythmic Drug Therapy for Atrial Fibrillation

Journal of the American Medical Association

Valve2011

STS/ACC TVT Registry

Society of Thoracic Surgeons / American College of Cardiology Transcatheter Valve Therapy Registry

Journal of the American College of Cardiology

Heart Failure2011

STICH

Surgical Treatment for Ischemic Heart Failure

New England Journal of Medicine

Heart Failure2018

VEST

Vest Prevention of Early Sudden Death Trial

New England Journal of Medicine

Heart Failure2017

MOMENTUM 3

Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy with HeartMate 3

New England Journal of Medicine

Valve2015

NOTION

Nordic Aortic Valve Intervention

Journal of the American Medical Association

Valve2017

SURTAVI

Surgical Replacement and Transcatheter Aortic Valve Implantation

New England Journal of Medicine

Coronary2018

ORBITA

Objective Randomised Blinded Investigation with Optimal Medical Therapy of Angioplasty in Stable Angina

The Lancet

Coronary2012

FAME 2

Fractional Flow Reserve versus Angiography for Multivessel Evaluation 2

New England Journal of Medicine

Evidence-Based Second Opinions

Every WhiteGloveMD report maps your case to current trial evidence and ACC/AHA guideline recommendations. Your Heart Team knows this literature.

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